NHRI Communications

NHRI researcher reports inadequate prenatal care utilization among women with and without methadone-treated opioid use disorders in Taiwan

PB May 20, 2019 May 20, 2019Highlights

Prenatal visits have been recognized as a window of opportunity to deliver healthcare and prevention to reduce obstetric complications and adverse birth outcomes, which is particularly important for the subpopulations characterized by socially disadvantaged backgrounds and high-risk conditions (e.g., women involved in illegal drugs). With the rising number of women…

NHRI licenses DBPR216, an anti-cancer developmental drug candidate, to Taivex Therapeutics Corp.

網站管理員 April 17, 2019 April 17, 2019Press Release

April 17, 2019 The National Health Research Institutes (NHRI) and Taivex Therapeutics Corp. (Taivex) are pleased to announce the technology transfer of DBPR216, a potential anti-cancer developmental drug candidate, effective April 8. NHRI’s licensing of DBPR216, a multi-targeted tyrosine kinase inhibitor, to Taivex will further the drug’s preclinical and clinical…

Weaving the Children’s Health Medical Network, Making a Bright Future for Children

網站管理員 April 10, 2019 April 10, 2019Press Release

April 10, 2019 Children are the treasures of their parents and the backbone of our country in the future. With the decline in Taiwan’s birth rate, how to strengthen the health welfare and medical care of children, so that children can grow up healthily, has become increasingly important. To help…

TLR2 promotes vascular smooth muscle cell chondrogenic differentiation and consequent calcification via the concerted actions of osteoprotegerin suppression and IL-6-mediated RANKL induction

PB April 3, 2019 April 3, 2019Highlights

Vascular smooth muscle cell (VSMC) transformation to an osteochondrogenic phenotype is an initial step toward arterial calcification, which is highly correlated with cardiovascular disease-related morbidity and mortality. TLR2 (toll-like receptor 2) plays a pathogenic role in the development of vascular diseases, but its regulation in calcification of arteries and VSMCs…

Does using a smartphone before bedtime affect sleep patterns?

PB April 1, 2019 April 1, 2019Press Release

April 1, 2019 The NHRI investigation shows smartphone use before bedtime delays circadian rhythm and reduces sleep times. The 2017 Nobel Prize in Physiology or Medicine Winning Theme “Controlling the molecular mechanisms for circadian rhythm”, pointed out that irregular sleep patterns may increase the risk of psychiatric and medical illnesses.…

PP4 deficiency leads to DNA replication stress that impairs immunoglobulin class switch efficiency and germinal center formation

PB March 27, 2019 March 27, 2019Highlights

A team led by Dr. Yu-Wen Su from the Immunology Research Center demonstrated that PP4 is indispensable for preventing DNA replication stress that could interfere with class switch recombination (CSR), thereby promoting antibody switching during the humoral immune response. PP4 is a serine/threonine phosphatase required for immunoglobulin (Ig) VDJ recombination…

Personal care products use and phthalate exposure levels among pregnant women

網站管理員 March 11, 2019 March 11, 2019Press Release

March 11, 2019 Phthalates are well-known endocrine disrupting chemicals that remain ubiquitous in the environment. Fetuses are susceptible to phthalates within sensitive windows of development. It is crucial to determine the major sources of phthalates to reduce exposure. The use of personal care products (PCPs) has been suggested as one…

NHRI signs MOU with Temasek Life Sciences Laboratory, Singapore

PB March 7, 2019 March 7, 2019Events

A team of representatives from NHRI signed a Memorandum of Understanding (MOU) with Temasek Life Sciences Laboratory (TLL), an affiliated research institute with the National University of Singapore and the Nanyang Technological University to jointly collaborate on research ventures in infectious diseases, vector-borne diseases biology, neuroscience and novel drug R&D…

NMDC Tainan Research Center welcomes visitor from Verily Life Science

PB January 21, 2019 January 21, 2019Visits

Dr. Nigel Snoad, product manager at Verily Life Science, a subsidiary of Google’s parent company Alphabet visited the National Mosquito-Borne Diseases Control (NMDC)’s Wolbachia-modified mosquito factory in Tainan research center on December, 2018 to promote the Debug Project and its novel technology. The Debug Project combines the expertise of scientists…

Glycemia and Healthy Aging: A Paradox Revealed by a Human Study of Aging

網站管理員 January 19, 2019 January 19, 2019Press Release

January 19, 2019 Healthy aging is the “process of developing and maintaining the functional ability that enables well-being in older age.” A recent work done by Dr. I-Chien Wu’s team and his collaborators revealed the surprisingly complex nature of the process. These new findings are recently published in the Journals…

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